Dr Jen Coleman
BSc (Southampton), MRes (KCL), PhD (KCL)
Postdoctoral Affiliate
College Roles
- Postdoctoral Affiliate
Contact
Biography
Dr Jennifer Coleman completed her BSc in Biology at University of Southampton in 2017, being awarded Faculty Merit and Gold Awards for her achievements during her undergraduate degree. She was then awarded a fully funded four-year studentship with the Medical Research Council Doctoral Training Partnership at King’s College London. Here, Dr Coleman was awarded an MRes in Biomedical and Translational Science, having undertaken multiple projects across a broad scope of biomedical research. She then completed her PhD in 2021 in Molecular and Cellular Oncology as part of a joint project between Prof. Agi Grigoriadis and Prof. Sasi Conte, working on understanding the functions of RNA-binding proteins in prostate cancer and osteosarcoma. Since 2022, Dr Coleman has continued this research within the field of neuro-oncology during her role as a Postdoctoral Research Associate in the Gilbertson Lab at the CRUK Cambridge Institute.
Research Interests
Dr Jennifer Coleman’s research aims to enhance our current understanding of how RNA-binding proteins, which are often abnormally expressed or mutated in cancer, contribute to oncogenesis. Her current research efforts focus on elucidating how mutations in genes coding for proteins that unwind RNA (helicases) contribute to the development of the childhood brain cancer, namely medulloblastoma. Dr Coleman is particularly focussed on understanding whether these mutated proteins act to promote oncogenesis through their functions in stress responses, translation and interactions with highly structured nucleic acids, with a view to unveil targetable mechanisms to combat brain cancers in children