BSc (Porto), MSc (Porto), PhD (Cantab)
- Special Supervisor in Natural Sciences (Biology of Cells)
- Postdoctoral Fellow / Research Associate in the Department of Biochemistry
Dr. Pedro Rebelo-Guiomar studied BSc Biochemistry at the University of Porto, Portugal, where he did an internship with Prof. Claudio Sunkel, working on the regulation and fidelity of cell division using Drosophila melanogaster (fruit fly) as model organism.
After attaining the degree with honours, Dr. Rebelo-Guiomar moved to the University of Coimbra, Portugal, studying alterations in Complex I associated with LHON, a relatively common mitochondrial disorder that affects 1 in 30,000-50,000 people.
Dr. Rebelo-Guiomar enrolled in the Graduate Program in Areas of Basic and Applied Biology (GABBA), at the University of Porto, Portugal, where he contacted with a multitude of research areas, and then moved to Cambridge to pursue a PhD at the MRC Mitochondrial Biology Unit / University of Cambridge, UK with Dr. Michal Minczuk, where he studied epigenetic modifications in mitochondrial RNA. Part of this work aimed at understanding how a single tiny methyl RNA modification impacts the assembly of the very large mitochondrial ribosome and, consequently, regulate mitochondrial translation. This work was awarded with the Milo Keynes Prize for Outstanding Thesis, has been published (https://www.nature.com/articles/s41467-022-28503-5), and was key to both the development of new methodologies and the establishment of local and international collaborations.
Dr. Rebelo-Guiomar is interested in mentoring, teaching and transmitting knowledge to newer generations, which brought him to Newnham College.
After a postdoc at the MRC Mitochondrial Biology Unit, Dr. Rebelo-Guiomar started a second postdoc to the group of Prof. Ben Luisi at the Department of Biochemistry, University of Cambridge, UK. Here, he is pursuing the study of RNA regulation with structural and mechanistic views, and developing new methodologies to advance the field.