BA (Hons), MA, PhD
Fellow (D), Director of Studies, Tutor
- Fellow (D)
- Director of Studies in Natural Sciences Biological (Parts II & III)
- Assistant Tutor (Postgraduates)
- Postgraduate Mentor
- University Associate Professor in Department of Pharmacology
Telephone: +44 (0) 1223 333964
Dr Catherine Lindon studied Biochemistry at the University of Oxford before moving to the ICRF in London for her PhD, then the Pasteur Institute in Paris for postdoctoral studies. She returned to the UK with a Wellcome Trust Advanced Training Fellowship to acquire expertise in live cell imaging of human cells, with Prof Jonathon Pines at the Gurdon Institute in Cambridge. She subsequently set up her own research programme with the support of a Career Development Award from the MRC. In 2008 Cath became a junior group leader in the Department of Genetics and in 2015 was appointed to a lectureship in the Department of Pharmacology.
Dr Catherine Lindon’s research lies in the field of cell biology. Her lab studies how the fundamental cellular process of ubiquitination regulates cell division. Ubiquitination acts to trigger elimination of unwanted components by the cell’s own destruction machinery. Cath’s current projects are focused on designing new strategies to subvert this destruction machinery, so that the cell is ‘tricked’ into getting rid of disease-causing proteins such as those giving rise to cancers. Her most recent publication – available here – illustrates how this can be achieved using small molecules known as ‘PROTACs’, a new and exciting type of pharmacological agent. In other projects, Cath collaborates with Prof Laura Itzhaki’s lab to design protein degrader tools that harness ubiquitination activity controlling cell division.